South Carolina Rental Cars

Start checking quotes in South Carolina to get a good deal for your next car rental with USA Rental Cars. We work together with the top auto rental providers in South Carolina, and now you can check rates side by side, all in one place. Travelers can get airport and rail station pick-up selections in addition to a wide range of other office locations in popular cities like Charleston, Greenville, and Myrtle Beach. Thinking about a one-way car rental? You can easily pick up in Charleston and drop off in Savannah, Georgia.

By having a car rental in South Carolina, nothing is off-limits. With so much to explore and do, you'll be happy you're in control of your schedule and allow for some improvisation. From economy to full-size SUVs and passenger vans, we've got the perfect vehicle for all your needs. Book and save money on your car with USA Rental Cars today.

Rental Car Suppliers we Work with in South Carolina

We partner with car rental providers in all 50 states in America. Regardless of whether you're preparing for a flight, arriving by train, or just searching for a rental for a road trip, we have got a practical pick-up place for you. Uncover great low rates in South Carolina from these suppliers plus more; get started assessing today.

Avis Car Rentals

Budget Rent a Car

Sixt Rent a Car

See More of South Carolina with a Rental Car

South Carolina was named after King Charles I of England, who first formed the English colony, Carolus being the Latin for "Charles." South Carolina became the eighth state to ratify the United States Constitution on May 23, 1788. It also became the first state to vote for secession from the Union on December 20, 1860. After the American Civil War, he was readmitted to the United States. States on June 25, 1868.

Visit Charleston - Charleston is the largest city in the US state of South Carolina, the county seat of Charleston, and the principal city in the Charleston-North Charleston - Summerville Metropolitan Statistical Area. The city is located just south of the geographic midpoint of the South Carolina coast at the Port of Charleston, an inlet to the Atlantic Ocean formed by the confluence of the Ashley, Cooper, and Wando rivers. Charleston had an estimated population of 137,566, according to the latest 2019 US Census Estimate. Book a Rental Car at CHS Airport

Visit Greenville - Greenville is a city in and the county seat of Greenville, South Carolina, United States. With an estimated population of 70,635 as of 2019, it is the sixth-largest city in the state. Greenville is located roughly midway between Atlanta, Georgia, and Charlotte, North Carolina, along Interstate 85, and its metropolitan area also includes Interstate 185 and 385. Greenville was the fourth fastest-growing city in the United States between 2015 and 2016, according to the US Census Bureau Book a Rental Car at GSP Airport

Visit Myrtle Beach - Ranked as the second fastest-growing metropolitan area in the country (according to 2018 census estimates), Myrtle Beach is one of the top tourism hubs in South Carolina and the United States. The city's warm, subtropical climate and long beaches attract some 14 million visitors each year. As of the 2010 census, the city's population was 27,109, and in 2019, the estimated population was 34,695. The Myrtle Beach metropolitan area had an estimated population in 2019 of 480,891. Book a Rental Car at MYR Airport